About this Study Set
This study set covers Biochemistry through
20 practice questions.
A collection of factual questions regarding history, discovery dates, and biochemical constants. Every question includes the correct answer so you can learn as you go — pick any format above to get started.
Questions & Answers
Browse all 20 questions from the
Biochemistry Historical Milestones and Quantitative Constants study set below.
Each question shows the correct answer — select a study format above to practice interactively.
1
In what year did James Sumner prove that enzymes are proteins by crystallizing urease?
-
A
1926
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B
1932
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C
1915
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D
1940
2
What is the standard free energy change (delta G'°) for the hydrolysis of ATP to ADP and inorganic phosphate at pH 7.0?
-
A
-15.5 kJ/mol
-
B
-30.5 kJ/mol
-
C
-45.2 kJ/mol
-
D
-10.0 kJ/mol
3
How many amino acid residues are typically contained in a single molecule of bovine insulin, as determined by Frederick Sanger in 1953?
4
Who was the scientist that first proposed the 'Induced Fit' model of enzyme-substrate interaction in 1958?
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A
Emil Fischer
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B
Daniel Koshland
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C
Linus Pauling
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D
John Kendrew
5
How many protons are pumped across the inner mitochondrial membrane for every molecule of NADH oxidized by Complex I?
6
In 1952, which researchers used a blender and a centrifuge to demonstrate that DNA is the genetic material of bacteriophages?
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A
Watson and Crick
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B
Hershey and Chase
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C
Meselson and Stahl
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D
Avery and MacLeod
7
What is the approximate pH of human blood in a healthy adult?
8
Frederick Sanger was awarded the Nobel Prize in Chemistry twice; in which year did he receive his second prize for DNA sequencing?
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A
1965
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B
1972
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C
1980
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D
1988
9
How many carbon atoms are present in a single molecule of glucose?
10
In the year 1937, which scientist described the citric acid cycle, also known as the Krebs cycle?
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A
Hans Krebs
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B
Otto Warburg
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C
Fritz Lipmann
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D
Carl Cori
11
What is the number of base pairs in one full turn of the B-DNA double helix?
-
A
8.5
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B
10.5
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C
12.0
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D
14.5
12
The protein hemoglobin consists of how many polypeptide subunits?
13
Linus Pauling published his seminal paper describing the alpha-helix structure of proteins in which year?
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A
1945
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B
1951
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C
1953
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D
1958
14
Approximately how many ATP molecules are produced from the complete aerobic oxidation of one molecule of glucose in eukaryotic cells?
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A
20-22
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B
28-30
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C
36-38
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D
40-42
15
Who received the 1962 Nobel Prize in Chemistry for determining the three-dimensional structures of globular proteins, specifically myoglobin?
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A
Max Perutz
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B
John Kendrew
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C
Dorothy Hodgkin
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D
Robert Woodward
16
What is the pKa of the carboxylic acid group in the amino acid glycine?
-
A
2.34
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B
4.25
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C
6.02
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D
9.60
17
In 1961, who proposed the Fluid Mosaic Model of biological membranes?
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A
Singer and Nicolson
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B
Davson and Danielli
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C
Robertson
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D
Gorter and Grendel
18
How many hydrogen bonds form between Guanine and Cytosine in a DNA base pair?
19
The enzyme catalase has a turnover number (kcat) of approximately how many reactions per second?
-
A
10^2
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B
10^4
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C
10^7
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D
10^10
20
Which scientist discovered the restriction enzymes that earned him a Nobel Prize in 1978?
-
A
Hamilton Smith
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B
Kary Mullis
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C
Arthur Kornberg
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D
Severo Ochoa
