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History of Organic Chemistry

Organic Chemistry

A collection of questions focused on the historical development and foundational milestones of organic chemistry.

history science chemistry

12 Questions Medium Ages 14+ Apr 3, 2026

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About this Study Set

This study set covers Organic Chemistry through 12 practice questions. A collection of questions focused on the historical development and foundational milestones of organic chemistry. Every question includes the correct answer so you can learn as you go — pick any format above to get started.

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Browse all 12 questions from the History of Organic Chemistry study set below. Each question shows the correct answer — select a study format above to practice interactively.

1 Which chemist is credited with synthesizing urea in 1828, effectively challenging the theory of vitalism?

A Friedrich Wöhler
B Antoine Lavoisier
C Dmitri Mendeleev
D John Dalton

2 Who proposed the theory of tetravalency of carbon, suggesting that carbon atoms can form four chemical bonds?

A August Kekulé
B Linus Pauling
C Gilbert N. Lewis
D Robert Boyle

3 In 1856, William Henry Perkin accidentally synthesized the first synthetic organic dye while attempting to create which substance?

A Quinine
B Penicillin
C Aspirin
D Caffeine

4 Which scientist discovered the hexagonal ring structure of benzene in 1865?

A August Kekulé
B Louis Pasteur
C Emil Fischer
D Jacobus Henricus van 't Hoff

5 The 1874 theory of stereochemistry, proposing the tetrahedral carbon atom, was independently developed by Jacobus Henricus van 't Hoff and whom?

A Joseph Achille Le Bel
B Marie Curie
C Ernest Rutherford
D Alfred Nobel

6 Which organic compound was the first to be synthesized from inorganic materials in a controlled laboratory experiment?

A Urea
B Methane
C Acetic acid
D Glucose

7 Who received the Nobel Prize in Chemistry in 1902 for his work on sugar and purine syntheses?

A Emil Fischer
B Adolf von Baeyer
C Victor Grignard
D Paul Sabatier

8 The Grignard reaction, which remains a staple in organic synthesis, was named after Victor Grignard, who discovered it in what year?

A 1900
B 1885
C 1915
D 1892

9 Who is known for the discovery of the 'lock and key' model of enzyme-substrate interaction in 1894?

A Emil Fischer
B Eduard Buchner
C Wilhelm Ostwald
D Max Planck

10 The 'Baeyer-Villiger oxidation' involves the conversion of a ketone to an ester and was discovered by Adolf von Baeyer and whom?

A Victor Villiger
B Otto Diels
C Kurt Alder
D Otto Wallach

11 Which chemist pioneered the study of the structure of proteins and received the Nobel Prize in 1958 for his work on insulin?

A Frederick Sanger
B Linus Pauling
C Dorothy Hodgkin
D Robert Woodward

12 In 1944, who developed the Woodward-Hoffmann rules to explain the conservation of orbital symmetry in chemical reactions?

A Robert Burns Woodward
B Roald Hoffmann
C Arthur C. Cope
D Louis Fieser

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